WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for each enriched gene sets are listed in this table.
For each gene set, the first row lists database name, gene set name , and corresponding gene set ID.
The second row lists the following statistics:
Finally, genes in the pathway are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:KEGG pathway       Name:Metabolic pathways       ID:01100
C=1130; O=185; E=29.45; R=6.28; rawP=2.08e-92; adjP=3.06e-90
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000163864 NA NMNAT3 nicotinamide nucleotide adenylyltransferase 3 349565 ENSG00000163864
2  ENSG00000187630 NA DHRS4L2 dehydrogenase/reductase (SDR family) member 4 like 2 317749 ENSG00000187630
3  ENSG00000165264 NA NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa 4712 ENSG00000165264
4  ENSG00000156467 NA UQCRB ubiquinol-cytochrome c reductase binding protein 7381 ENSG00000156467
5  ENSG00000100142 NA POLR2F polymerase (RNA) II (DNA directed) polypeptide F 5435 ENSG00000100142
6  ENSG00000184076 NA UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X 29796 ENSG00000184076
7  ENSG00000078070 NA MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha) 56922 ENSG00000078070
8  ENSG00000148672 NA GLUD1 glutamate dehydrogenase 1 2746 ENSG00000148672
9  ENSG00000156885 NA COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 1339 ENSG00000156885
10  ENSG00000154723 NA ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 522 ENSG00000154723
11  ENSG00000006695 NA COX10 COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase (yeast) 1352 ENSG00000006695
12  ENSG00000105552 NA BCAT2 branched chain amino-acid transaminase 2, mitochondrial 587 ENSG00000105552
13  ENSG00000125166 NA GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) 2806 ENSG00000125166
14  ENSG00000135390 NA ATP5G2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) 517 ENSG00000135390
15  ENSG00000140740 NA UQCRC2 ubiquinol-cytochrome c reductase core protein II 7385 ENSG00000140740
16  ENSG00000166136 NA NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa 4714 ENSG00000166136
17  ENSG00000116353 NA MECR mitochondrial trans-2-enoyl-CoA reductase 51102 ENSG00000116353
18  ENSG00000114378 NA HYAL1 hyaluronoglucosaminidase 1 3373 ENSG00000114378
19  ENSG00000172340 NA SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 8801 ENSG00000172340
20  ENSG00000147684 NA NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa 4715 ENSG00000147684
21  ENSG00000160194 NA NDUFV3 NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa 4731 ENSG00000160194
22  ENSG00000151093 NA OXSM 3-oxoacyl-ACP synthase, mitochondrial 54995 ENSG00000151093
23  ENSG00000184983 NA NDUFA6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa 4700 ENSG00000184983
24  ENSG00000130414 NA NDUFA10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa 4705 ENSG00000130414
25  ENSG00000091140 NA DLD dihydrolipoamide dehydrogenase 1738 ENSG00000091140
26  ENSG00000158864 NA NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) 4720 ENSG00000158864
27  ENSG00000131828 NA PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 5160 ENSG00000131828
28  ENSG00000122971 NA ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain 35 ENSG00000122971
29  ENSG00000109390 NA NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa 4717 ENSG00000109390
30  ENSG00000103356 NA EARS2 glutamyl-tRNA synthetase 2, mitochondrial (putative) 124454 ENSG00000103356
31  ENSG00000000419 NA DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit 8813 ENSG00000000419
32  ENSG00000091483 NA FH fumarate hydratase 2271 ENSG00000091483
33  ENSG00000120254 NA MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like 25902 ENSG00000120254
34  ENSG00000109586 NA GALNT7 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7) 51809 ENSG00000109586
35  ENSG00000119689 NA DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) 1743 ENSG00000119689
36  ENSG00000168291 NA PDHB pyruvate dehydrogenase (lipoamide) beta 5162 ENSG00000168291
37  ENSG00000148334 NA PTGES2 prostaglandin E synthase 2 80142 ENSG00000148334
38  ENSG00000116459 NA ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 515 ENSG00000116459
39  ENSG00000119537 NA KDSR 3-ketodihydrosphingosine reductase 2531 ENSG00000119537
40  ENSG00000112992 NA NNT nicotinamide nucleotide transhydrogenase 23530 ENSG00000112992
41  ENSG00000149925 NA ALDOA aldolase A, fructose-bisphosphate 226 ENSG00000149925
42  ENSG00000023330 NA ALAS1 aminolevulinate, delta-, synthase 1 211 ENSG00000023330
43  ENSG00000213619 NA NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) 4722 ENSG00000213619
44  ENSG00000178741 NA COX5A cytochrome c oxidase subunit Va 9377 ENSG00000178741
45  ENSG00000173660 NA UQCRH ubiquinol-cytochrome c reductase hinge protein 7388 ENSG00000173660
46  ENSG00000119421 NA NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa 4702 ENSG00000119421
47  ENSG00000126267 NA COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) 1340 ENSG00000126267
48  ENSG00000104879 NA CKM creatine kinase, muscle 1158 ENSG00000104879
49  ENSG00000135940 NA COX5B cytochrome c oxidase subunit Vb 1329 ENSG00000135940
50  ENSG00000113790 NA EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase 1962 ENSG00000113790
51  ENSG00000145494 NA NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) 4726 ENSG00000145494
52  ENSG00000072506 NA HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 3028 ENSG00000072506
53  ENSG00000131143 NA COX4I1 cytochrome c oxidase subunit IV isoform 1 1327 ENSG00000131143
54  ENSG00000189043 NA NDUFA4 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa 4697 ENSG00000189043
55  ENSG00000179085 NA DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3 54344 ENSG00000179085
56  ENSG00000123739 NA PLA2G12A phospholipase A2, group XIIA 81579 ENSG00000123739
57  ENSG00000164919 NA COX6C cytochrome c oxidase subunit VIc 1345 ENSG00000164919
58  ENSG00000185100 NA ADSSL1 adenylosuccinate synthase like 1 122622 ENSG00000185100
59  ENSG00000115286 NA NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) 374291 ENSG00000115286
60  ENSG00000164258 NA NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) 4724 ENSG00000164258
61  ENSG00000167863 NA ATP5H ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d 10476 ENSG00000167863
62  ENSG00000108515 NA ENO3 enolase 3 (beta, muscle) 2027 ENSG00000108515
63  ENSG00000090266 NA NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa 4708 ENSG00000090266
64  ENSG00000179091 NA CYC1 cytochrome c-1 1537 ENSG00000179091
65  ENSG00000166165 NA CKB creatine kinase, brain 1152 ENSG00000166165
66  ENSG00000127540 NA UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI 10975 ENSG00000127540
67  ENSG00000151498 NA ACAD8 acyl-CoA dehydrogenase family, member 8 27034 ENSG00000151498
68  ENSG00000047249 NA ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H 51606 ENSG00000047249
69  ENSG00000132423 NA COQ3 coenzyme Q3 homolog, methyltransferase (S. cerevisiae) 51805 ENSG00000132423
70  ENSG00000131844 NA MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta) 64087 ENSG00000131844
71  ENSG00000159199 NA ATP5G1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9) 516 ENSG00000159199
72  ENSG00000136143 NA SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit 8803 ENSG00000136143
73  ENSG00000135778 NA NTPCR nucleoside-triphosphatase, cancer-related 84284 ENSG00000135778
74  ENSG00000105258 NA POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa 5438 ENSG00000105258
75  ENSG00000204228 NA HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 7923 ENSG00000204228
76  ENSG00000173614 NA NMNAT1 nicotinamide nucleotide adenylyltransferase 1 64802 ENSG00000173614
77  ENSG00000172331 NA BPGM 2,3-bisphosphoglycerate mutase 669 ENSG00000172331
78  ENSG00000175198 NA PCCA propionyl CoA carboxylase, alpha polypeptide 5095 ENSG00000175198
79  ENSG00000067829 NA IDH3G isocitrate dehydrogenase 3 (NAD+) gamma 3421 ENSG00000067829
80  ENSG00000116171 NA SCP2 sterol carrier protein 2 6342 ENSG00000116171
81  ENSG00000129187 NA DCTD dCMP deaminase 1635 ENSG00000129187
82  ENSG00000067225 NA PKM pyruvate kinase, muscle 5315 ENSG00000067225
83  ENSG00000157326 NA DHRS4 dehydrogenase/reductase (SDR family) member 4 10901 ENSG00000157326
84  ENSG00000140990 NA NDUFB10 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa 4716 ENSG00000140990
85  ENSG00000138495 NA COX17 COX17 cytochrome c oxidase assembly homolog (S. cerevisiae) 10063 ENSG00000138495
86  ENSG00000117118 NA SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 6390 ENSG00000117118
87  ENSG00000066926 NA FECH ferrochelatase 2235 ENSG00000066926
88  ENSG00000144182 NA LIPT1 lipoyltransferase 1 51601 ENSG00000144182
89  ENSG00000143641 NA GALNT2 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2) 2590 ENSG00000143641
90  ENSG00000006530 NA AGK acylglycerol kinase 55750 ENSG00000006530
91  ENSG00000184207 NA PGP phosphoglycolate phosphatase 283871 ENSG00000184207
92  ENSG00000005075 NA POLR2J polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa 5439 ENSG00000005075
93  ENSG00000165629 NA ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 509 ENSG00000165629
94  ENSG00000149380 NA P4HA3 prolyl 4-hydroxylase, alpha polypeptide III 283208 ENSG00000149380
95  ENSG00000100294 NA MCAT malonyl CoA:ACP acyltransferase (mitochondrial) 27349 ENSG00000100294
96  ENSG00000014641 NA MDH1 malate dehydrogenase 1, NAD (soluble) 4190 ENSG00000014641
97  ENSG00000152234 NA ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle 498 ENSG00000152234
98  ENSG00000105220 NA GPI glucose-6-phosphate isomerase 2821 ENSG00000105220
99  ENSG00000172893 NA DHCR7 7-dehydrocholesterol reductase 1717 ENSG00000172893
100  ENSG00000154930 NA ACSS1 acyl-CoA synthetase short-chain family member 1 84532 ENSG00000154930
101  ENSG00000072778 NA ACADVL acyl-CoA dehydrogenase, very long chain 37 ENSG00000072778
102  ENSG00000151366 NA NDUFC2 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa 4718 ENSG00000151366
103  ENSG00000128609 NA NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa 4698 ENSG00000128609
104  ENSG00000178802 NA MPI mannose phosphate isomerase 4351 ENSG00000178802
105  ENSG00000163541 NA SUCLG1 succinate-CoA ligase, alpha subunit 8802 ENSG00000163541
106  ENSG00000146701 NA MDH2 malate dehydrogenase 2, NAD (mitochondrial) 4191 ENSG00000146701
107  ENSG00000112981 NA NME5 NME/NM23 family member 5 8382 ENSG00000112981
108  ENSG00000103489 NA XYLT1 xylosyltransferase I 64131 ENSG00000103489
109  ENSG00000126088 NA UROD uroporphyrinogen decarboxylase 7389 ENSG00000126088
110  ENSG00000136521 NA NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa 4711 ENSG00000136521
111  ENSG00000131730 NA CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 1160 ENSG00000131730
112  ENSG00000182054 NA IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 3418 ENSG00000182054
113  ENSG00000169020 NA ATP5I ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E 521 ENSG00000169020
114  ENSG00000004779 NA NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa 4706 ENSG00000004779
115  ENSG00000172954 NA LCLAT1 lysocardiolipin acyltransferase 1 253558 ENSG00000172954
116  ENSG00000073578 NA SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 6389 ENSG00000073578
117  ENSG00000119013 NA NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa 4709 ENSG00000119013
118  ENSG00000115652 NA UXS1 UDP-glucuronate decarboxylase 1 80146 ENSG00000115652
119  ENSG00000169021 NA UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 7386 ENSG00000169021
120  ENSG00000157881 NA PANK4 pantothenate kinase 4 55229 ENSG00000157881
121  ENSG00000197943 NA PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) 5336 ENSG00000197943
122  ENSG00000062485 NA CS citrate synthase 1431 ENSG00000062485
123  ENSG00000120053 NA GOT1 glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) 2805 ENSG00000120053
124  ENSG00000139428 NA MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 326625 ENSG00000139428
125  ENSG00000171130 NA ATP6V0E2 ATPase, H+ transporting V0 subunit e2 155066 ENSG00000171130
126  ENSG00000124370 NA MCEE methylmalonyl CoA epimerase 84693 ENSG00000124370
127  ENSG00000139180 NA NDUFA9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa 4704 ENSG00000139180
128  ENSG00000127184 NA COX7C cytochrome c oxidase subunit VIIc 1350 ENSG00000127184
129  ENSG00000111640 NA GAPDH glyceraldehyde-3-phosphate dehydrogenase 2597 ENSG00000111640
130  ENSG00000177700 NA POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa 5441 ENSG00000177700
131  ENSG00000164405 NA UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa 27089 ENSG00000164405
132  ENSG00000122729 NA ACO1 aconitase 1, soluble 48 ENSG00000122729
133  ENSG00000173085 NA COQ2 coenzyme Q2 homolog, prenyltransferase (yeast) 27235 ENSG00000173085
134  ENSG00000124172 NA ATP5E ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit 514 ENSG00000124172
135  ENSG00000156958 NA GALK2 galactokinase 2 2585 ENSG00000156958
136  ENSG00000183648 NA NDUFB1 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa 4707 ENSG00000183648
137  ENSG00000110435 NA PDHX pyruvate dehydrogenase complex, component X 8050 ENSG00000110435
138  ENSG00000099624 NA ATP5D ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit 513 ENSG00000099624
139  ENSG00000204370 NA SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 6392 ENSG00000204370
140  ENSG00000100412 NA ACO2 aconitase 2, mitochondrial 50 ENSG00000100412
141  ENSG00000137106 NA GRHPR glyoxylate reductase/hydroxypyruvate reductase 9380 ENSG00000137106
142  ENSG00000169738 NA DCXR dicarbonyl/L-xylulose reductase 51181 ENSG00000169738
143  ENSG00000160211 NA G6PD glucose-6-phosphate dehydrogenase 2539 ENSG00000160211
144  ENSG00000125356 NA NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa 4694 ENSG00000125356
145  ENSG00000099795 NA NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa 4713 ENSG00000099795
146  ENSG00000111669 NA TPI1 triosephosphate isomerase 1 7167 ENSG00000111669
147  ENSG00000153574 NA RPIA ribose 5-phosphate isomerase A 22934 ENSG00000153574
148  ENSG00000148090 NA AUH AU RNA binding protein/enoyl-CoA hydratase 549 ENSG00000148090
149  ENSG00000023228 NA NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) 4719 ENSG00000023228
150  ENSG00000143252 NA SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa 6391 ENSG00000143252
151  ENSG00000151376 NA ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial 10873 ENSG00000151376
152  ENSG00000121897 NA LIAS lipoic acid synthetase 11019 ENSG00000121897
153  ENSG00000110955 NA ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 506 ENSG00000110955
154  ENSG00000060971 NA ACAA1 acetyl-CoA acyltransferase 1 30 ENSG00000060971
155  ENSG00000119723 NA COQ6 coenzyme Q6 homolog, monooxygenase (S. cerevisiae) 51004 ENSG00000119723
156  ENSG00000147155 NA EBP emopamil binding protein (sterol isomerase) 10682 ENSG00000147155
157  ENSG00000197894 NA ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 128 ENSG00000197894
158  ENSG00000167792 NA NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa 4723 ENSG00000167792
159  ENSG00000131495 NA NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa 4695 ENSG00000131495
160  ENSG00000065518 NA NDUFB4 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa 4710 ENSG00000065518
161  ENSG00000117594 NA HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 3290 ENSG00000117594
162  ENSG00000185808 NA PIGP phosphatidylinositol glycan anchor biosynthesis, class P 51227 ENSG00000185808
163  ENSG00000110717 NA NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) 4728 ENSG00000110717
164  ENSG00000131174 NA COX7B cytochrome c oxidase subunit VIIb 1349 ENSG00000131174
165  ENSG00000205309 NA NT5M 5',3'-nucleotidase, mitochondrial 56953 ENSG00000205309
166  ENSG00000170906 NA NDUFA3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa 4696 ENSG00000170906
167  ENSG00000111716 NA LDHB lactate dehydrogenase B 3945 ENSG00000111716
168  ENSG00000108439 NA PNPO pyridoxamine 5'-phosphate oxidase 55163 ENSG00000108439
169  ENSG00000167283 NA ATP5L ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G 10632 ENSG00000167283
170  ENSG00000114054 NA PCCB propionyl CoA carboxylase, beta polypeptide 5096 ENSG00000114054
171  ENSG00000111275 NA ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 217 ENSG00000111275
172  ENSG00000127884 NA ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial 1892 ENSG00000127884
173  ENSG00000010256 NA UQCRC1 ubiquinol-cytochrome c reductase core protein I 7384 ENSG00000010256
174  ENSG00000241468 NA ATP5J2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2 9551 ENSG00000241468
175  ENSG00000138796 NA HADH hydroxyacyl-CoA dehydrogenase 3033 ENSG00000138796
176  ENSG00000154518 NA ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9) 518 ENSG00000154518
177  ENSG00000161533 NA ACOX1 acyl-CoA oxidase 1, palmitoyl 51 ENSG00000161533
178  ENSG00000107317 NA PTGDS prostaglandin D2 synthase 21kDa (brain) 5730 ENSG00000107317
179  ENSG00000176340 NA COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 1351 ENSG00000176340
180  ENSG00000170266 NA GLB1 galactosidase, beta 1 2720 ENSG00000170266
181  ENSG00000168653 NA NDUFS5 NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) 4725 ENSG00000168653
182  ENSG00000101365 NA IDH3B isocitrate dehydrogenase 3 (NAD+) beta 3420 ENSG00000101365
183  ENSG00000156110 NA ADK adenosine kinase 132 ENSG00000156110
184  ENSG00000141504 NA SAT2 spermidine/spermine N1-acetyltransferase family member 2 112483 ENSG00000141504
185  ENSG00000241837 NA ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit 539 ENSG00000241837


Database:KEGG pathway       Name:Oxidative phosphorylation       ID:00190
C=132; O=79; E=3.44; R=22.96; rawP=3.84e-90; adjP=2.82e-88
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000151366 NA NDUFC2 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa 4718 ENSG00000151366
2  ENSG00000128609 NA NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa 4698 ENSG00000128609
3  ENSG00000165264 NA NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa 4712 ENSG00000165264
4  ENSG00000156467 NA UQCRB ubiquinol-cytochrome c reductase binding protein 7381 ENSG00000156467
5  ENSG00000184076 NA UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X 29796 ENSG00000184076
6  ENSG00000161281 NA COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) 1346 ENSG00000161281
7  ENSG00000136521 NA NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa 4711 ENSG00000136521
8  ENSG00000004779 NA NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa 4706 ENSG00000004779
9  ENSG00000169020 NA ATP5I ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E 521 ENSG00000169020
10  ENSG00000156885 NA COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 1339 ENSG00000156885
11  ENSG00000147123 NA NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa 54539 ENSG00000147123
12  ENSG00000154723 NA ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 522 ENSG00000154723
13  ENSG00000006695 NA COX10 COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase (yeast) 1352 ENSG00000006695
14  ENSG00000073578 NA SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 6389 ENSG00000073578
15  ENSG00000119013 NA NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa 4709 ENSG00000119013
16  ENSG00000169021 NA UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 7386 ENSG00000169021
17  ENSG00000135390 NA ATP5G2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) 517 ENSG00000135390
18  ENSG00000140740 NA UQCRC2 ubiquinol-cytochrome c reductase core protein II 7385 ENSG00000140740
19  ENSG00000166136 NA NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa 4714 ENSG00000166136
20  ENSG00000147684 NA NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa 4715 ENSG00000147684
21  ENSG00000160194 NA NDUFV3 NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa 4731 ENSG00000160194
22  ENSG00000184983 NA NDUFA6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa 4700 ENSG00000184983
23  ENSG00000130414 NA NDUFA10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa 4705 ENSG00000130414
24  ENSG00000158864 NA NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) 4720 ENSG00000158864
25  ENSG00000171130 NA ATP6V0E2 ATPase, H+ transporting V0 subunit e2 155066 ENSG00000171130
26  ENSG00000139180 NA NDUFA9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa 4704 ENSG00000139180
27  ENSG00000109390 NA NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa 4717 ENSG00000109390
28  ENSG00000127184 NA COX7C cytochrome c oxidase subunit VIIc 1350 ENSG00000127184
29  ENSG00000164405 NA UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa 27089 ENSG00000164405
30  ENSG00000124172 NA ATP5E ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit 514 ENSG00000124172
31  ENSG00000183648 NA NDUFB1 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa 4707 ENSG00000183648
32  ENSG00000099624 NA ATP5D ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit 513 ENSG00000099624
33  ENSG00000116459 NA ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 515 ENSG00000116459
34  ENSG00000204370 NA SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 6392 ENSG00000204370
35  ENSG00000125356 NA NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa 4694 ENSG00000125356
36  ENSG00000138777 NA PPA2 pyrophosphatase (inorganic) 2 27068 ENSG00000138777
37  ENSG00000213619 NA NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) 4722 ENSG00000213619
38  ENSG00000178741 NA COX5A cytochrome c oxidase subunit Va 9377 ENSG00000178741
39  ENSG00000173660 NA UQCRH ubiquinol-cytochrome c reductase hinge protein 7388 ENSG00000173660
40  ENSG00000099795 NA NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa 4713 ENSG00000099795
41  ENSG00000119421 NA NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa 4702 ENSG00000119421
42  ENSG00000126267 NA COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) 1340 ENSG00000126267
43  ENSG00000135940 NA COX5B cytochrome c oxidase subunit Vb 1329 ENSG00000135940
44  ENSG00000023228 NA NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) 4719 ENSG00000023228
45  ENSG00000143252 NA SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa 6391 ENSG00000143252
46  ENSG00000145494 NA NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) 4726 ENSG00000145494
47  ENSG00000189043 NA NDUFA4 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa 4697 ENSG00000189043
48  ENSG00000131143 NA COX4I1 cytochrome c oxidase subunit IV isoform 1 1327 ENSG00000131143
49  ENSG00000110955 NA ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 506 ENSG00000110955
50  ENSG00000164919 NA COX6C cytochrome c oxidase subunit VIc 1345 ENSG00000164919
51  ENSG00000115286 NA NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) 374291 ENSG00000115286
52  ENSG00000112695 NA COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) 1347 ENSG00000112695
53  ENSG00000164258 NA NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) 4724 ENSG00000164258
54  ENSG00000167792 NA NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa 4723 ENSG00000167792
55  ENSG00000131495 NA NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa 4695 ENSG00000131495
56  ENSG00000065518 NA NDUFB4 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa 4710 ENSG00000065518
57  ENSG00000167863 NA ATP5H ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d 10476 ENSG00000167863
58  ENSG00000090266 NA NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa 4708 ENSG00000090266
59  ENSG00000110717 NA NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) 4728 ENSG00000110717
60  ENSG00000127540 NA UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI 10975 ENSG00000127540
61  ENSG00000179091 NA CYC1 cytochrome c-1 1537 ENSG00000179091
62  ENSG00000131174 NA COX7B cytochrome c oxidase subunit VIIb 1349 ENSG00000131174
63  ENSG00000047249 NA ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H 51606 ENSG00000047249
64  ENSG00000184752 NA NDUFA12 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12 55967 ENSG00000184752
65  ENSG00000170906 NA NDUFA3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa 4696 ENSG00000170906
66  ENSG00000159199 NA ATP5G1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9) 516 ENSG00000159199
67  ENSG00000167283 NA ATP5L ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G 10632 ENSG00000167283
68  ENSG00000010256 NA UQCRC1 ubiquinol-cytochrome c reductase core protein I 7384 ENSG00000010256
69  ENSG00000241468 NA ATP5J2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2 9551 ENSG00000241468
70  ENSG00000140990 NA NDUFB10 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa 4716 ENSG00000140990
71  ENSG00000117118 NA SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 6390 ENSG00000117118
72  ENSG00000138495 NA COX17 COX17 cytochrome c oxidase assembly homolog (S. cerevisiae) 10063 ENSG00000138495
73  ENSG00000154518 NA ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9) 518 ENSG00000154518
74  ENSG00000165629 NA ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 509 ENSG00000165629
75  ENSG00000115944 NA COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like 9167 ENSG00000115944
76  ENSG00000176340 NA COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 1351 ENSG00000176340
77  ENSG00000168653 NA NDUFS5 NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) 4725 ENSG00000168653
78  ENSG00000152234 NA ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle 498 ENSG00000152234
79  ENSG00000241837 NA ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit 539 ENSG00000241837


Database:KEGG pathway       Name:Parkinson's disease       ID:05012
C=130; O=77; E=3.39; R=22.73; rawP=2.31e-87; adjP=1.13e-85
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000151366 NA NDUFC2 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa 4718 ENSG00000151366
2  ENSG00000128609 NA NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa 4698 ENSG00000128609
3  ENSG00000165264 NA NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa 4712 ENSG00000165264
4  ENSG00000156467 NA UQCRB ubiquinol-cytochrome c reductase binding protein 7381 ENSG00000156467
5  ENSG00000184076 NA UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X 29796 ENSG00000184076
6  ENSG00000161281 NA COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) 1346 ENSG00000161281
7  ENSG00000136521 NA NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa 4711 ENSG00000136521
8  ENSG00000004779 NA NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa 4706 ENSG00000004779
9  ENSG00000156885 NA COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 1339 ENSG00000156885
10  ENSG00000147123 NA NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa 54539 ENSG00000147123
11  ENSG00000154723 NA ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 522 ENSG00000154723
12  ENSG00000073578 NA SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 6389 ENSG00000073578
13  ENSG00000116288 NA PARK7 parkinson protein 7 11315 ENSG00000116288
14  ENSG00000119013 NA NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa 4709 ENSG00000119013
15  ENSG00000169021 NA UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 7386 ENSG00000169021
16  ENSG00000135390 NA ATP5G2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) 517 ENSG00000135390
17  ENSG00000140740 NA UQCRC2 ubiquinol-cytochrome c reductase core protein II 7385 ENSG00000140740
18  ENSG00000166136 NA NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa 4714 ENSG00000166136
19  ENSG00000078668 NA VDAC3 voltage-dependent anion channel 3 7419 ENSG00000078668
20  ENSG00000147684 NA NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa 4715 ENSG00000147684
21  ENSG00000160194 NA NDUFV3 NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa 4731 ENSG00000160194
22  ENSG00000184983 NA NDUFA6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa 4700 ENSG00000184983
23  ENSG00000130414 NA NDUFA10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa 4705 ENSG00000130414
24  ENSG00000158864 NA NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) 4720 ENSG00000158864
25  ENSG00000139180 NA NDUFA9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa 4704 ENSG00000139180
26  ENSG00000109390 NA NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa 4717 ENSG00000109390
27  ENSG00000127184 NA COX7C cytochrome c oxidase subunit VIIc 1350 ENSG00000127184
28  ENSG00000164405 NA UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa 27089 ENSG00000164405
29  ENSG00000165637 NA VDAC2 voltage-dependent anion channel 2 7417 ENSG00000165637
30  ENSG00000124172 NA ATP5E ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit 514 ENSG00000124172
31  ENSG00000183648 NA NDUFB1 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa 4707 ENSG00000183648
32  ENSG00000213585 NA VDAC1 voltage-dependent anion channel 1 7416 ENSG00000213585
33  ENSG00000099624 NA ATP5D ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit 513 ENSG00000099624
34  ENSG00000116459 NA ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 515 ENSG00000116459
35  ENSG00000204370 NA SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 6392 ENSG00000204370
36  ENSG00000151729 NA SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 291 ENSG00000151729
37  ENSG00000125356 NA NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa 4694 ENSG00000125356
38  ENSG00000178741 NA COX5A cytochrome c oxidase subunit Va 9377 ENSG00000178741
39  ENSG00000213619 NA NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) 4722 ENSG00000213619
40  ENSG00000173660 NA UQCRH ubiquinol-cytochrome c reductase hinge protein 7388 ENSG00000173660
41  ENSG00000099795 NA NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa 4713 ENSG00000099795
42  ENSG00000119421 NA NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa 4702 ENSG00000119421
43  ENSG00000126267 NA COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) 1340 ENSG00000126267
44  ENSG00000135940 NA COX5B cytochrome c oxidase subunit Vb 1329 ENSG00000135940
45  ENSG00000023228 NA NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) 4719 ENSG00000023228
46  ENSG00000143252 NA SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa 6391 ENSG00000143252
47  ENSG00000145494 NA NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) 4726 ENSG00000145494
48  ENSG00000189043 NA NDUFA4 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa 4697 ENSG00000189043
49  ENSG00000172115 NA CYCS cytochrome c, somatic 54205 ENSG00000172115
50  ENSG00000131143 NA COX4I1 cytochrome c oxidase subunit IV isoform 1 1327 ENSG00000131143
51  ENSG00000110955 NA ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 506 ENSG00000110955
52  ENSG00000164919 NA COX6C cytochrome c oxidase subunit VIc 1345 ENSG00000164919
53  ENSG00000115286 NA NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) 374291 ENSG00000115286
54  ENSG00000112695 NA COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) 1347 ENSG00000112695
55  ENSG00000164258 NA NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) 4724 ENSG00000164258
56  ENSG00000167792 NA NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa 4723 ENSG00000167792
57  ENSG00000131495 NA NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa 4695 ENSG00000131495
58  ENSG00000065518 NA NDUFB4 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa 4710 ENSG00000065518
59  ENSG00000167863 NA ATP5H ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d 10476 ENSG00000167863
60  ENSG00000090266 NA NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa 4708 ENSG00000090266
61  ENSG00000110717 NA NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) 4728 ENSG00000110717
62  ENSG00000179091 NA CYC1 cytochrome c-1 1537 ENSG00000179091
63  ENSG00000127540 NA UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI 10975 ENSG00000127540
64  ENSG00000131174 NA COX7B cytochrome c oxidase subunit VIIb 1349 ENSG00000131174
65  ENSG00000184752 NA NDUFA12 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12 55967 ENSG00000184752
66  ENSG00000170906 NA NDUFA3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa 4696 ENSG00000170906
67  ENSG00000159199 NA ATP5G1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9) 516 ENSG00000159199
68  ENSG00000010256 NA UQCRC1 ubiquinol-cytochrome c reductase core protein I 7384 ENSG00000010256
69  ENSG00000140990 NA NDUFB10 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa 4716 ENSG00000140990
70  ENSG00000117118 NA SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 6390 ENSG00000117118
71  ENSG00000154518 NA ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9) 518 ENSG00000154518
72  ENSG00000165629 NA ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 509 ENSG00000165629
73  ENSG00000115944 NA COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like 9167 ENSG00000115944
74  ENSG00000176340 NA COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 1351 ENSG00000176340
75  ENSG00000168653 NA NDUFS5 NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) 4725 ENSG00000168653
76  ENSG00000152234 NA ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle 498 ENSG00000152234
77  ENSG00000241837 NA ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit 539 ENSG00000241837


Database:KEGG pathway       Name:Huntington's disease       ID:05016
C=183; O=83; E=4.77; R=17.40; rawP=4.80e-81; adjP=1.76e-79
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000151366 NA NDUFC2 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa 4718 ENSG00000151366
2  ENSG00000128609 NA NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa 4698 ENSG00000128609
3  ENSG00000165264 NA NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa 4712 ENSG00000165264
4  ENSG00000156467 NA UQCRB ubiquinol-cytochrome c reductase binding protein 7381 ENSG00000156467
5  ENSG00000100142 NA POLR2F polymerase (RNA) II (DNA directed) polypeptide F 5435 ENSG00000100142
6  ENSG00000184076 NA UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X 29796 ENSG00000184076
7  ENSG00000161281 NA COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) 1346 ENSG00000161281
8  ENSG00000136521 NA NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa 4711 ENSG00000136521
9  ENSG00000004779 NA NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa 4706 ENSG00000004779
10  ENSG00000156885 NA COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 1339 ENSG00000156885
11  ENSG00000169375 NA SIN3A SIN3 transcription regulator homolog A (yeast) 25942 ENSG00000169375
12  ENSG00000147123 NA NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa 54539 ENSG00000147123
13  ENSG00000154723 NA ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 522 ENSG00000154723
14  ENSG00000073578 NA SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 6389 ENSG00000073578
15  ENSG00000119013 NA NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa 4709 ENSG00000119013
16  ENSG00000169021 NA UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 7386 ENSG00000169021
17  ENSG00000135390 NA ATP5G2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) 517 ENSG00000135390
18  ENSG00000140740 NA UQCRC2 ubiquinol-cytochrome c reductase core protein II 7385 ENSG00000140740
19  ENSG00000166136 NA NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa 4714 ENSG00000166136
20  ENSG00000078668 NA VDAC3 voltage-dependent anion channel 3 7419 ENSG00000078668
21  ENSG00000147684 NA NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa 4715 ENSG00000147684
22  ENSG00000160194 NA NDUFV3 NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa 4731 ENSG00000160194
23  ENSG00000184983 NA NDUFA6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa 4700 ENSG00000184983
24  ENSG00000130414 NA NDUFA10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa 4705 ENSG00000130414
25  ENSG00000158864 NA NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) 4720 ENSG00000158864
26  ENSG00000100246 NA DNAL4 dynein, axonemal, light chain 4 10126 ENSG00000100246
27  ENSG00000139180 NA NDUFA9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa 4704 ENSG00000139180
28  ENSG00000142168 NA SOD1 superoxide dismutase 1, soluble 6647 ENSG00000142168
29  ENSG00000109390 NA NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa 4717 ENSG00000109390
30  ENSG00000127184 NA COX7C cytochrome c oxidase subunit VIIc 1350 ENSG00000127184
31  ENSG00000177700 NA POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa 5441 ENSG00000177700
32  ENSG00000164405 NA UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa 27089 ENSG00000164405
33  ENSG00000165637 NA VDAC2 voltage-dependent anion channel 2 7417 ENSG00000165637
34  ENSG00000124172 NA ATP5E ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit 514 ENSG00000124172
35  ENSG00000183648 NA NDUFB1 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa 4707 ENSG00000183648
36  ENSG00000213585 NA VDAC1 voltage-dependent anion channel 1 7416 ENSG00000213585
37  ENSG00000099624 NA ATP5D ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit 513 ENSG00000099624
38  ENSG00000116459 NA ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 515 ENSG00000116459
39  ENSG00000204370 NA SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 6392 ENSG00000204370
40  ENSG00000151729 NA SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 291 ENSG00000151729
41  ENSG00000125356 NA NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa 4694 ENSG00000125356
42  ENSG00000178741 NA COX5A cytochrome c oxidase subunit Va 9377 ENSG00000178741
43  ENSG00000213619 NA NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) 4722 ENSG00000213619
44  ENSG00000173660 NA UQCRH ubiquinol-cytochrome c reductase hinge protein 7388 ENSG00000173660
45  ENSG00000099795 NA NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa 4713 ENSG00000099795
46  ENSG00000119421 NA NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa 4702 ENSG00000119421
47  ENSG00000126267 NA COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) 1340 ENSG00000126267
48  ENSG00000135940 NA COX5B cytochrome c oxidase subunit Vb 1329 ENSG00000135940
49  ENSG00000023228 NA NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) 4719 ENSG00000023228
50  ENSG00000143252 NA SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa 6391 ENSG00000143252
51  ENSG00000145494 NA NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) 4726 ENSG00000145494
52  ENSG00000189043 NA NDUFA4 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa 4697 ENSG00000189043
53  ENSG00000172115 NA CYCS cytochrome c, somatic 54205 ENSG00000172115
54  ENSG00000131143 NA COX4I1 cytochrome c oxidase subunit IV isoform 1 1327 ENSG00000131143
55  ENSG00000110955 NA ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 506 ENSG00000110955
56  ENSG00000164919 NA COX6C cytochrome c oxidase subunit VIc 1345 ENSG00000164919
57  ENSG00000115286 NA NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) 374291 ENSG00000115286
58  ENSG00000112695 NA COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) 1347 ENSG00000112695
59  ENSG00000164258 NA NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) 4724 ENSG00000164258
60  ENSG00000167792 NA NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa 4723 ENSG00000167792
61  ENSG00000131495 NA NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa 4695 ENSG00000131495
62  ENSG00000065518 NA NDUFB4 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa 4710 ENSG00000065518
63  ENSG00000167863 NA ATP5H ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d 10476 ENSG00000167863
64  ENSG00000090266 NA NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa 4708 ENSG00000090266
65  ENSG00000110717 NA NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) 4728 ENSG00000110717
66  ENSG00000179091 NA CYC1 cytochrome c-1 1537 ENSG00000179091
67  ENSG00000127540 NA UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI 10975 ENSG00000127540
68  ENSG00000131174 NA COX7B cytochrome c oxidase subunit VIIb 1349 ENSG00000131174
69  ENSG00000184752 NA NDUFA12 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12 55967 ENSG00000184752
70  ENSG00000170906 NA NDUFA3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa 4696 ENSG00000170906
71  ENSG00000159199 NA ATP5G1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9) 516 ENSG00000159199
72  ENSG00000105258 NA POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa 5438 ENSG00000105258
73  ENSG00000010256 NA UQCRC1 ubiquinol-cytochrome c reductase core protein I 7384 ENSG00000010256
74  ENSG00000140990 NA NDUFB10 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa 4716 ENSG00000140990
75  ENSG00000117118 NA SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 6390 ENSG00000117118
76  ENSG00000005075 NA POLR2J polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa 5439 ENSG00000005075
77  ENSG00000154518 NA ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9) 518 ENSG00000154518
78  ENSG00000165629 NA ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 509 ENSG00000165629
79  ENSG00000115944 NA COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like 9167 ENSG00000115944
80  ENSG00000176340 NA COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 1351 ENSG00000176340
81  ENSG00000152234 NA ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle 498 ENSG00000152234
82  ENSG00000168653 NA NDUFS5 NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) 4725 ENSG00000168653
83  ENSG00000241837 NA ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit 539 ENSG00000241837


Database:KEGG pathway       Name:Alzheimer's disease       ID:05010
C=167; O=78; E=4.35; R=17.92; rawP=1.81e-77; adjP=5.32e-76
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000151366 NA NDUFC2 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa 4718 ENSG00000151366
2  ENSG00000128609 NA NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa 4698 ENSG00000128609
3  ENSG00000165264 NA NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa 4712 ENSG00000165264
4  ENSG00000156467 NA UQCRB ubiquinol-cytochrome c reductase binding protein 7381 ENSG00000156467
5  ENSG00000184076 NA UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X 29796 ENSG00000184076
6  ENSG00000161281 NA COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) 1346 ENSG00000161281
7  ENSG00000136521 NA NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa 4711 ENSG00000136521
8  ENSG00000004779 NA NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa 4706 ENSG00000004779
9  ENSG00000156885 NA COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 1339 ENSG00000156885
10  ENSG00000147123 NA NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa 54539 ENSG00000147123
11  ENSG00000154723 NA ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 522 ENSG00000154723
12  ENSG00000073578 NA SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 6389 ENSG00000073578
13  ENSG00000119013 NA NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa 4709 ENSG00000119013
14  ENSG00000169021 NA UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 7386 ENSG00000169021
15  ENSG00000135390 NA ATP5G2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) 517 ENSG00000135390
16  ENSG00000140740 NA UQCRC2 ubiquinol-cytochrome c reductase core protein II 7385 ENSG00000140740
17  ENSG00000166136 NA NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa 4714 ENSG00000166136
18  ENSG00000147684 NA NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa 4715 ENSG00000147684
19  ENSG00000160194 NA NDUFV3 NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa 4731 ENSG00000160194
20  ENSG00000184983 NA NDUFA6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa 4700 ENSG00000184983
21  ENSG00000130414 NA NDUFA10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa 4705 ENSG00000130414
22  ENSG00000158864 NA NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) 4720 ENSG00000158864
23  ENSG00000159593 NA NAE1 NEDD8 activating enzyme E1 subunit 1 8883 ENSG00000159593
24  ENSG00000139180 NA NDUFA9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa 4704 ENSG00000139180
25  ENSG00000109390 NA NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa 4717 ENSG00000109390
26  ENSG00000127184 NA COX7C cytochrome c oxidase subunit VIIc 1350 ENSG00000127184
27  ENSG00000111640 NA GAPDH glyceraldehyde-3-phosphate dehydrogenase 2597 ENSG00000111640
28  ENSG00000164405 NA UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa 27089 ENSG00000164405
29  ENSG00000123384 NA LRP1 low density lipoprotein receptor-related protein 1 4035 ENSG00000123384
30  ENSG00000124172 NA ATP5E ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit 514 ENSG00000124172
31  ENSG00000183648 NA NDUFB1 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa 4707 ENSG00000183648
32  ENSG00000099624 NA ATP5D ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit 513 ENSG00000099624
33  ENSG00000116459 NA ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 515 ENSG00000116459
34  ENSG00000204370 NA SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 6392 ENSG00000204370
35  ENSG00000125356 NA NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa 4694 ENSG00000125356
36  ENSG00000213619 NA NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) 4722 ENSG00000213619
37  ENSG00000178741 NA COX5A cytochrome c oxidase subunit Va 9377 ENSG00000178741
38  ENSG00000173660 NA UQCRH ubiquinol-cytochrome c reductase hinge protein 7388 ENSG00000173660
39  ENSG00000099795 NA NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa 4713 ENSG00000099795
40  ENSG00000119421 NA NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa 4702 ENSG00000119421
41  ENSG00000126267 NA COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) 1340 ENSG00000126267
42  ENSG00000135940 NA COX5B cytochrome c oxidase subunit Vb 1329 ENSG00000135940
43  ENSG00000023228 NA NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) 4719 ENSG00000023228
44  ENSG00000143252 NA SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa 6391 ENSG00000143252
45  ENSG00000186318 NA BACE1 beta-site APP-cleaving enzyme 1 23621 ENSG00000265969 ENSG00000186318
46  ENSG00000145494 NA NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) 4726 ENSG00000145494
47  ENSG00000072506 NA HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 3028 ENSG00000072506
48  ENSG00000189043 NA NDUFA4 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa 4697 ENSG00000189043
49  ENSG00000172115 NA CYCS cytochrome c, somatic 54205 ENSG00000172115
50  ENSG00000131143 NA COX4I1 cytochrome c oxidase subunit IV isoform 1 1327 ENSG00000131143
51  ENSG00000110955 NA ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 506 ENSG00000110955
52  ENSG00000164919 NA COX6C cytochrome c oxidase subunit VIc 1345 ENSG00000164919
53  ENSG00000115286 NA NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) 374291 ENSG00000115286
54  ENSG00000112695 NA COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) 1347 ENSG00000112695
55  ENSG00000164258 NA NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) 4724 ENSG00000164258
56  ENSG00000167792 NA NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa 4723 ENSG00000167792
57  ENSG00000131495 NA NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa 4695 ENSG00000131495
58  ENSG00000065518 NA NDUFB4 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa 4710 ENSG00000065518
59  ENSG00000167863 NA ATP5H ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d 10476 ENSG00000167863
60  ENSG00000090266 NA NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa 4708 ENSG00000090266
61  ENSG00000130203 NA APOE apolipoprotein E 348 ENSG00000130203
62  ENSG00000110717 NA NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) 4728 ENSG00000110717
63  ENSG00000179091 NA CYC1 cytochrome c-1 1537 ENSG00000179091
64  ENSG00000127540 NA UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI 10975 ENSG00000127540
65  ENSG00000131174 NA COX7B cytochrome c oxidase subunit VIIb 1349 ENSG00000131174
66  ENSG00000184752 NA NDUFA12 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12 55967 ENSG00000184752
67  ENSG00000170906 NA NDUFA3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa 4696 ENSG00000170906
68  ENSG00000159199 NA ATP5G1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9) 516 ENSG00000159199
69  ENSG00000010256 NA UQCRC1 ubiquinol-cytochrome c reductase core protein I 7384 ENSG00000010256
70  ENSG00000140990 NA NDUFB10 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa 4716 ENSG00000140990
71  ENSG00000117118 NA SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 6390 ENSG00000117118
72  ENSG00000154518 NA ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9) 518 ENSG00000154518
73  ENSG00000165629 NA ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 509 ENSG00000165629
74  ENSG00000115944 NA COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like 9167 ENSG00000115944
75  ENSG00000176340 NA COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 1351 ENSG00000176340
76  ENSG00000168653 NA NDUFS5 NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) 4725 ENSG00000168653
77  ENSG00000152234 NA ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle 498 ENSG00000152234
78  ENSG00000241837 NA ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit 539 ENSG00000241837


Database:KEGG pathway       Name:Citrate cycle (TCA cycle)       ID:00020
C=30; O=20; E=0.78; R=25.58; rawP=4.16e-25; adjP=1.02e-23
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000136143 NA SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit 8803 ENSG00000136143
2  ENSG00000131828 NA PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 5160 ENSG00000131828
3  ENSG00000163541 NA SUCLG1 succinate-CoA ligase, alpha subunit 8802 ENSG00000163541
4  ENSG00000143252 NA SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa 6391 ENSG00000143252
5  ENSG00000146701 NA MDH2 malate dehydrogenase 2, NAD (mitochondrial) 4191 ENSG00000146701
6  ENSG00000067829 NA IDH3G isocitrate dehydrogenase 3 (NAD+) gamma 3421 ENSG00000067829
7  ENSG00000122729 NA ACO1 aconitase 1, soluble 48 ENSG00000122729
8  ENSG00000091483 NA FH fumarate hydratase 2271 ENSG00000091483
9  ENSG00000182054 NA IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 3418 ENSG00000182054
10  ENSG00000119689 NA DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) 1743 ENSG00000119689
11  ENSG00000168291 NA PDHB pyruvate dehydrogenase (lipoamide) beta 5162 ENSG00000168291
12  ENSG00000073578 NA SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 6389 ENSG00000073578
13  ENSG00000204370 NA SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 6392 ENSG00000204370
14  ENSG00000117118 NA SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 6390 ENSG00000117118
15  ENSG00000100412 NA ACO2 aconitase 2, mitochondrial 50 ENSG00000100412
16  ENSG00000062485 NA CS citrate synthase 1431 ENSG00000062485
17  ENSG00000172340 NA SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 8801 ENSG00000172340
18  ENSG00000014641 NA MDH1 malate dehydrogenase 1, NAD (soluble) 4190 ENSG00000014641
19  ENSG00000101365 NA IDH3B isocitrate dehydrogenase 3 (NAD+) beta 3420 ENSG00000101365
20  ENSG00000091140 NA DLD dihydrolipoamide dehydrogenase 1738 ENSG00000091140


Database:KEGG pathway       Name:Cardiac muscle contraction       ID:04260
C=77; O=26; E=2.01; R=12.96; rawP=3.23e-22; adjP=6.78e-21
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000114854 NA TNNC1 troponin C type 1 (slow) 7134 ENSG00000114854
2  ENSG00000135940 NA COX5B cytochrome c oxidase subunit Vb 1329 ENSG00000135940
3  ENSG00000127184 NA COX7C cytochrome c oxidase subunit VIIc 1350 ENSG00000127184
4  ENSG00000129991 NA TNNI3 troponin I type 3 (cardiac) 7137 ENSG00000129991
5  ENSG00000198467 NA TPM2 tropomyosin 2 (beta) 7169 ENSG00000198467
6  ENSG00000156467 NA UQCRB ubiquinol-cytochrome c reductase binding protein 7381 ENSG00000156467
7  ENSG00000164405 NA UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa 27089 ENSG00000164405
8  ENSG00000184076 NA UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X 29796 ENSG00000184076
9  ENSG00000161281 NA COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) 1346 ENSG00000161281
10  ENSG00000131143 NA COX4I1 cytochrome c oxidase subunit IV isoform 1 1327 ENSG00000131143
11  ENSG00000010256 NA UQCRC1 ubiquinol-cytochrome c reductase core protein I 7384 ENSG00000010256
12  ENSG00000156885 NA COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 1339 ENSG00000156885
13  ENSG00000164919 NA COX6C cytochrome c oxidase subunit VIc 1345 ENSG00000164919
14  ENSG00000157445 NA CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3 55799 ENSG00000157445
15  ENSG00000112695 NA COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) 1347 ENSG00000112695
16  ENSG00000169021 NA UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 7386 ENSG00000169021
17  ENSG00000115944 NA COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like 9167 ENSG00000115944
18  ENSG00000176340 NA COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 1351 ENSG00000176340
19  ENSG00000140740 NA UQCRC2 ubiquinol-cytochrome c reductase core protein II 7385 ENSG00000140740
20  ENSG00000178741 NA COX5A cytochrome c oxidase subunit Va 9377 ENSG00000178741
21  ENSG00000173660 NA UQCRH ubiquinol-cytochrome c reductase hinge protein 7388 ENSG00000173660
22  ENSG00000179091 NA CYC1 cytochrome c-1 1537 ENSG00000179091
23  ENSG00000127540 NA UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI 10975 ENSG00000127540
24  ENSG00000131174 NA COX7B cytochrome c oxidase subunit VIIb 1349 ENSG00000131174
25  ENSG00000126267 NA COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) 1340 ENSG00000126267
26  ENSG00000160808 NA MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow 4634 ENSG00000160808


Database:KEGG pathway       Name:Valine, leucine and isoleucine degradation       ID:00280
C=44; O=17; E=1.15; R=14.82; rawP=3.71e-16; adjP=6.82e-15
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000124370 NA MCEE methylmalonyl CoA epimerase 84693 ENSG00000124370
2  ENSG00000122971 NA ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain 35 ENSG00000122971
3  ENSG00000114054 NA PCCB propionyl CoA carboxylase, beta polypeptide 5096 ENSG00000114054
4  ENSG00000148090 NA AUH AU RNA binding protein/enoyl-CoA hydratase 549 ENSG00000148090
5  ENSG00000111275 NA ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 217 ENSG00000111275
6  ENSG00000113790 NA EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase 1962 ENSG00000113790
7  ENSG00000175198 NA PCCA propionyl CoA carboxylase, alpha polypeptide 5095 ENSG00000175198
8  ENSG00000127884 NA ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial 1892 ENSG00000127884
9  ENSG00000072506 NA HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 3028 ENSG00000072506
10  ENSG00000078070 NA MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha) 56922 ENSG00000078070
11  ENSG00000060971 NA ACAA1 acetyl-CoA acyltransferase 1 30 ENSG00000060971
12  ENSG00000105552 NA BCAT2 branched chain amino-acid transaminase 2, mitochondrial 587 ENSG00000105552
13  ENSG00000083720 NA OXCT1 3-oxoacid CoA transferase 1 5019 ENSG00000083720
14  ENSG00000138796 NA HADH hydroxyacyl-CoA dehydrogenase 3033 ENSG00000138796
15  ENSG00000151498 NA ACAD8 acyl-CoA dehydrogenase family, member 8 27034 ENSG00000151498
16  ENSG00000091140 NA DLD dihydrolipoamide dehydrogenase 1738 ENSG00000091140
17  ENSG00000131844 NA MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta) 64087 ENSG00000131844


Database:KEGG pathway       Name:Peroxisome       ID:04146
C=79; O=19; E=2.06; R=9.23; rawP=1.39e-13; adjP=2.27e-12
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000162735 NA PEX19 peroxisomal biogenesis factor 19 5824 ENSG00000162735
2  ENSG00000142168 NA SOD1 superoxide dismutase 1, soluble 6647 ENSG00000142168
3  ENSG00000113790 NA EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase 1962 ENSG00000113790
4  ENSG00000203797 NA DDO D-aspartate oxidase 8528 ENSG00000203797
5  ENSG00000116171 NA SCP2 sterol carrier protein 2 6342 ENSG00000116171
6  ENSG00000176894 NA PXMP2 peroxisomal membrane protein 2, 22kDa 5827 ENSG00000176894
7  ENSG00000182054 NA IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 3418 ENSG00000182054
8  ENSG00000060971 NA ACAA1 acetyl-CoA acyltransferase 1 30 ENSG00000060971
9  ENSG00000104823 NA ECH1 enoyl CoA hydratase 1, peroxisomal 1891 ENSG00000104823
10  ENSG00000157326 NA DHRS4 dehydrogenase/reductase (SDR family) member 4 10901 ENSG00000157326
11  ENSG00000213965 NA NUDT19 nudix (nucleoside diphosphate linked moiety X)-type motif 19 390916 ENSG00000213965
12  ENSG00000131779 NA PEX11B peroxisomal biogenesis factor 11 beta 8799 ENSG00000131779
13  ENSG00000197448 NA GSTK1 glutathione S-transferase kappa 1 373156 ENSG00000197448
14  ENSG00000112357 NA PEX7 peroxisomal biogenesis factor 7 5191 ENSG00000112357
15  ENSG00000095321 NA CRAT carnitine O-acetyltransferase 1384 ENSG00000095321
16  ENSG00000161533 NA ACOX1 acyl-CoA oxidase 1, palmitoyl 51 ENSG00000161533
17  ENSG00000126432 NA PRDX5 peroxiredoxin 5 25824 ENSG00000126432
18  ENSG00000116906 NA GNPAT glyceronephosphate O-acyltransferase 8443 ENSG00000116906
19  ENSG00000198721 NA ECI2 enoyl-CoA delta isomerase 2 10455 ENSG00000198721


Database:KEGG pathway       Name:Pyruvate metabolism       ID:00620
C=40; O=14; E=1.04; R=13.43; rawP=7.61e-13; adjP=1.12e-11
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000131828 NA PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 5160 ENSG00000131828
2  ENSG00000137106 NA GRHPR glyoxylate reductase/hydroxypyruvate reductase 9380 ENSG00000137106
3  ENSG00000111275 NA ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 217 ENSG00000111275
4  ENSG00000146701 NA MDH2 malate dehydrogenase 2, NAD (mitochondrial) 4191 ENSG00000146701
5  ENSG00000151376 NA ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial 10873 ENSG00000151376
6  ENSG00000124767 NA GLO1 glyoxalase I 2739 ENSG00000124767
7  ENSG00000170634 NA ACYP2 acylphosphatase 2, muscle type 98 ENSG00000170634
8  ENSG00000014641 NA MDH1 malate dehydrogenase 1, NAD (soluble) 4190 ENSG00000014641
9  ENSG00000067225 NA PKM pyruvate kinase, muscle 5315 ENSG00000067225
10  ENSG00000091140 NA DLD dihydrolipoamide dehydrogenase 1738 ENSG00000091140
11  ENSG00000154930 NA ACSS1 acyl-CoA synthetase short-chain family member 1 84532 ENSG00000154930
12  ENSG00000166816 NA LDHD lactate dehydrogenase D 197257 ENSG00000166816
13  ENSG00000168291 NA PDHB pyruvate dehydrogenase (lipoamide) beta 5162 ENSG00000168291
14  ENSG00000111716 NA LDHB lactate dehydrogenase B 3945 ENSG00000111716




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).